I'm happy to see Naval mentioned a bunch, bummed that no one has mentioned the 'After On' podcast by Rob Reid [1]. Rob Reid interviews Naval, ep. 44 & 45, the 2 part interview/discussion focuses on X-Risks, whether the long-term is going to exist for our species, automated assassination markets, drone swarms ending commercial air travel as we know it, fucking awesome. My dad is a 71 year old doctor, a little aspy, loved the podcast so much he shamed me into supporting it on Patreon. The podcast is on a hiatus at the moment, the back catalog is well worth exploring. The Fermi's Paradox episode with Stephen Webb, the Aubrey de Grey episode, and Rick Doblin (of MAPS) episodes are magic. I also highly recommend Rob Reids sci-fi book named 'After On', particularly if you work in tech in the bay area.
[1] https://after-on.com/