As an Aspie/ADD, I have never passed any formal interview, even for an intern position (sic!). (You can compare and contrast it with my GitHub/Resume/blog to make a judgment.)
Fortunately, many times (even for mid-size companies or research institutes) the hiring was less formal. For small startups, where it is informal, I didn't feel at a disadvantage. For big, I don't believe I can pass through the first filter.
It seems that there are so many hidden assumptions people take on: what should be on Resume, how should one present oneself, where it is fine (or de facto expected) to exaggerate one's accomplishments or hide one's weaknesses. And that an irrational feeling of being weird is often an instant no-hire. Moreover, many symptoms od ADD are taken for laziness, sloppiness, or lack of motivation. Many symptoms of Aspie are taken for rudeness, ill intentions or trying to dominate (breaking a social rule => (s)he thinks (s)he is above it).
(I've heard it so many times about people interviewing others, as "(s)he is smart, passed all test, but weird, I don't like to work with her/him". At this point, it is systemic discrimination. I the same places, remarks about one's ethnicity or gender wouldn't pass (rightfully!). Sadly, other areas of discrimination like age or class are given a pass.)
At the same time, I know a lot of people good at "big talks", and making a good impression, who got hired almost everywhere. Also, they make it easy to persuade the right people to give them recommendation letters, even if their collaboration was minimal.
Fortunately, many times (even for mid-size companies or research institutes) the hiring was less formal. For small startups, where it is informal, I didn't feel at a disadvantage. For big, I don't believe I can pass through the first filter.
It seems that there are so many hidden assumptions people take on: what should be on Resume, how should one present oneself, where it is fine (or de facto expected) to exaggerate one's accomplishments or hide one's weaknesses. And that an irrational feeling of being weird is often an instant no-hire. Moreover, many symptoms od ADD are taken for laziness, sloppiness, or lack of motivation. Many symptoms of Aspie are taken for rudeness, ill intentions or trying to dominate (breaking a social rule => (s)he thinks (s)he is above it).
(I've heard it so many times about people interviewing others, as "(s)he is smart, passed all test, but weird, I don't like to work with her/him". At this point, it is systemic discrimination. I the same places, remarks about one's ethnicity or gender wouldn't pass (rightfully!). Sadly, other areas of discrimination like age or class are given a pass.)
At the same time, I know a lot of people good at "big talks", and making a good impression, who got hired almost everywhere. Also, they make it easy to persuade the right people to give them recommendation letters, even if their collaboration was minimal.