I do not sense that you've read my comment critically. Because, for one thing, it says nothing about adverse effects increasing. Rather, the idea proposed is that effects can
cluster together in time, without increasing in absolute quantity.
When a vaccine is administered, the probability of some reaction follows some kind of curve that initially rises, and then drops off. If two weeks have passed and no reaction has occurred, then the probability has already fallen off to a long tail that is next to zero.
With me so far?
So now if several vaccines are started at the same time, the "payload" parts of respective curves are superimposed now. If any effects occur, they will almost certainly occur within the next few days or couple of weeks of the administration. And that is the same period for all vaccines in the bunch.
It's almost unimaginable that synchronized start does not create a clustering effect of the probability of adverse effects.
However, in most cases that clustering probably desirable. If the adverse effects are boxed to within the same week for all vaccines, then people will experience less overall "down time" like fewer days off work or school.
Thus, don't have three vaccines just before going on a dream vacation booked months in advance. In fact, maybe don't have any vaccines at all (other than something related to the vacation destination!)
When a vaccine is administered, the probability of some reaction follows some kind of curve that initially rises, and then drops off. If two weeks have passed and no reaction has occurred, then the probability has already fallen off to a long tail that is next to zero.
With me so far?
So now if several vaccines are started at the same time, the "payload" parts of respective curves are superimposed now. If any effects occur, they will almost certainly occur within the next few days or couple of weeks of the administration. And that is the same period for all vaccines in the bunch.
It's almost unimaginable that synchronized start does not create a clustering effect of the probability of adverse effects.
However, in most cases that clustering probably desirable. If the adverse effects are boxed to within the same week for all vaccines, then people will experience less overall "down time" like fewer days off work or school.
Thus, don't have three vaccines just before going on a dream vacation booked months in advance. In fact, maybe don't have any vaccines at all (other than something related to the vacation destination!)