Not even in the same universe. Containers using some managed k8s (EKS, or GKE) cluster with helm is ridiculously easier to manage a dynamic sets of applications running than bare amis. I have a k8s cluster that runs across >1k ec2 instances where I have thousand of containers running various jobs. I can apply/delete any massive deployment across that literally in seconds. with a single command.
The layers make it a lot lot easier here.