I can't speak for the person you're responding to, but as someone who also started (and failed) a moonshot company I can chime in. To grossly oversimplify, failure (especially when you put everything into something) can make people jaded. The breaking point for everyone is different, but eventually you just don't want to try the pie-in-the-sky idea because you remember how painful the failure is, how many years of your life you lost, how many relationships damaged or ruined, personal debts accrued, etcetera.
At some point you want to minimize stress and just take an easy job that pays a shitload of money and you value your free time more than your career.
At some point you want to minimize stress and just take an easy job that pays a shitload of money and you value your free time more than your career.