Even if the Python solution is vastly superior, there is significantly more people who know or want to learn Javascript, so if your game is to sell stuff, it's only reasonable to pick the bigger market, and the kind of complexity you're talking about is very common to modern Javascript.
Most devs know some Javascript and as complex as the current js ecosystem is, it still seems like those devs would prefer to deal with some libs in a language they already know rather than learn a completely new one.
Even if the Python solution is vastly superior, there is significantly more people who know or want to learn Javascript, so if your game is to sell stuff, it's only reasonable to pick the bigger market, and the kind of complexity you're talking about is very common to modern Javascript.
Most devs know some Javascript and as complex as the current js ecosystem is, it still seems like those devs would prefer to deal with some libs in a language they already know rather than learn a completely new one.