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Comment by burning_hamster

> experimentally solve multiple high-resolution 3D models per week

I thought this was only true if you already have a structure; otherwise you typically run into the [phase problem](https://en.wikipedia.org/wiki/Phase_problem), which is often a significant hurdle. But I haven't done much biochemistry in years, so there might be better approaches than MAD/MIR/etc. that make the phase problem a non-issue.

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