Philadelphia is a really great city to live and work in my opinion. Good city density but not overcrowded, walkable, affordable, good public transit, diverse. Public schools aren't the best currently so many families with young children do end up moving to the immediate suburbs where schools are some of the best. Lots of colleges (UPenn, Drexel, Temple) to recruit from as you expand.
I'm not sure Philly would rank highest on the "could be helped" aspect since it has a decent business sector already, but the tech (especially startup) scene is just getting started compared to the tons of healthcare and finance firms.
I'm not sure Philly would rank highest on the "could be helped" aspect since it has a decent business sector already, but the tech (especially startup) scene is just getting started compared to the tons of healthcare and finance firms.