Comment by nextos

Yes, I used to deal with email like that. Gnus + Dovecot + Sieve.

I find Notmuch + mbsync more satisfying because of efficiency and simplicity. It's a serverless setup, config files are small, and it's very quick.

Both Notmuch and Mu4e have good Org integration, so if you want to explore that route it shouldn't be a show-stopper.