Comment by VladTheImplier

They are where form and contour matters, which you can't always deduce from a orthographic 3 Panel view. In my current case the form and thickness variation of nerves in Parkinson's patients is looked at and analyzed. Since nerve curve through space like worms, looking at curvature in raw image data is unpractical, especially since it's not always apparent whether you look at the cross section at an angle.