> It seems like the key to making medical progress is realizing that not all treatments are "one size fits all"
The medical community has realized this, and been tackling this problem for a few millennia. Hippocrates addressed the topic.
>and figuring out why treatments that are safe and effective for some people are unsafe for others.
That’s the hard part. It’s why we pay attention to how we construct patient recruitment, sample demographics, assess the metabolic pathways by which a drug is processed and study genetic variants in those pathways, develop biologics with different types of chimeric proteins, retrospectively analyze adverse events for patterns, etc.
Each and every one of those things that are standard elements of modern medicine and rational drug design are about understanding variability in drug response. We haven’t perfected this yet - nor are we close. Anyone who wishes to lend a brain cell is welcome.
The medical community has realized this, and been tackling this problem for a few millennia. Hippocrates addressed the topic.
>and figuring out why treatments that are safe and effective for some people are unsafe for others.
That’s the hard part. It’s why we pay attention to how we construct patient recruitment, sample demographics, assess the metabolic pathways by which a drug is processed and study genetic variants in those pathways, develop biologics with different types of chimeric proteins, retrospectively analyze adverse events for patterns, etc.
Each and every one of those things that are standard elements of modern medicine and rational drug design are about understanding variability in drug response. We haven’t perfected this yet - nor are we close. Anyone who wishes to lend a brain cell is welcome.