I'm left-handed and grew up writing English. Except in the cases that I take special care to hold my hand somewhat awkwardly off the page, virtually everything I've ever written has some amount of smudging. I have vivid memories of my graphite-coated hand in primary school. In addition, it's harder to see the flow of the word; your hand covers up everything but the last letter or two.
It's clearly something that impacts different people in different ways.
It's clearly something that impacts different people in different ways.