I am a neurologist. this is actually the exact opposite of what you should care about, which is "does it work to treat ___"
In this trial, and 99% of other trials, there is no mechanism provided by the study, only a measurement of causality (which is the same thing as effectiveness).
The authors may think they know based on other, prior, basic science research (as they are postulating here), but it does not affect the conclusions of the trial ( whether they do or don't (or even if they are wrong).
Obviously it's intellectually satisfying to understand WHY, but it's not as important as "is it true?"
In this trial, and 99% of other trials, there is no mechanism provided by the study, only a measurement of causality (which is the same thing as effectiveness).
The authors may think they know based on other, prior, basic science research (as they are postulating here), but it does not affect the conclusions of the trial ( whether they do or don't (or even if they are wrong).
Obviously it's intellectually satisfying to understand WHY, but it's not as important as "is it true?"