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Comment by Diggity

HIV is notable for its ability to create "hidden reservoirs". Some recent cure attempts have been aimed at intentionally "kicking" the hidden reservoirs in order to flush them out. For this reason I mentioned inducing leukemia as it would replicate the circumstances of the Berlin Patient.

For additional follow up, there have been additional bone marrow transplant attempts in somewhat similar circumstances with bone marrow that did not contain the mutation.

Further reading:

Hidden reservoirs: https://www.nature.com/news/hidden-hiv-reservoirs-exposed-by...

The "Boston Patients": https://www.nature.com/news/hopes-of-hiv-cure-in-boston-pati...

parent Diggity 8 years ago

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