Ask YC: Do unpopular languages affect acquisition?

I read somewhere that when choosing a language for your start-up you should pick the most powerful language available (e.g. why Viaweb picked lisp). This sounds obvious, but I can't help but feel like if you build a great product using unpopular language X and your competitor builds a slightly (or even significantly) worse product with popular language Y, then a buyer would prefer your competitor's product for the reasons large companies prefer popular languages in the first place. Has this ever actually been a problem for somebody?