Comment by chris_t

If the underlying motivation for understanding or judging is to figure out what public policy to adopt, then the choice of what to do is simply what works best. If some people are irredeemable and locking them away forever ends up creating the safest and healthiest society for the most people, then judge away. If it turns out that helping people and understanding them where possible works better, do that. Most progress seems to me to originate in moving from the former to the latter, in moving more people out of the "irredeemable" category.