Ayahuasca is a South American brew consisting of two plants one consisting of a MAOI and another of DMT (the exact plant genus differs). DMT without a MAOI gets broken down by the blood brain barrier, so its not efficient without the MAOI.
The MAOI however puts dietary restrictions before the drug is being administered, and also makes the drug last vastly longer. Without the MAOI, the DMT wouldn't last long (IIRC even less long than Salvia). That might be an interesting use case.
Apart from that, there's all the time research on tryptamines [1] (MDMA, LSD, psilocybin, etc) used to treat mental diseases and personality disorders. The advantage synthetic drugs have is they're easier to standardise. I'm not sure why you'd want to research MAOI + DMT instead of the ones already mentioned? What advantages could it have over those?
The MAOI however puts dietary restrictions before the drug is being administered, and also makes the drug last vastly longer. Without the MAOI, the DMT wouldn't last long (IIRC even less long than Salvia). That might be an interesting use case.
Apart from that, there's all the time research on tryptamines [1] (MDMA, LSD, psilocybin, etc) used to treat mental diseases and personality disorders. The advantage synthetic drugs have is they're easier to standardise. I'm not sure why you'd want to research MAOI + DMT instead of the ones already mentioned? What advantages could it have over those?
[1] http://psychedelic-information-theory.com/Psychedelic-Pharma...