Loss rate for space launches is largely due to the fact that the systems are essentially munitions (i.e. expendable, single-use) and flight rates are very low.
Rocket failures for crewed rocket launches are extremely rare, occurring once every couple decades. It's hard to improve on that because low flight rates make data very hard to come by. Airplanes fail much more often in absolute terms, giving you a lot more data to work with (especially when combined with near-misses) allowing you bring the relative failure rate very low.
Increase flight rates by 5 orders of magnitude, and you may be able to increase reliability by, say, 4 orders of magnitude.
Rocket failures for crewed rocket launches are extremely rare, occurring once every couple decades. It's hard to improve on that because low flight rates make data very hard to come by. Airplanes fail much more often in absolute terms, giving you a lot more data to work with (especially when combined with near-misses) allowing you bring the relative failure rate very low.
Increase flight rates by 5 orders of magnitude, and you may be able to increase reliability by, say, 4 orders of magnitude.