Even at 50% the speed of light, adding in a fudge factor for acceleration/deceleration, you're still talking about a trip time of 50 yrs. Even if you go all Neon Genesis and send 15 year olds on the journey, they'll be at retirement age by the time they arrive.
In other words, you'd almost definitely have to send a generation ship. Which means you'd have to have already figured things like artificial gravity, giving birth and raising children in space, etc. It wouldn't be too hard to imagine taking earth values for day/night and gravity, and then gradually over 50 years adjusting them so that, by the time you arrive, you'd have acclimatized to those values on the new world.
Also, nuclear sub crews live 18 hour days, so it's definitely doable.
In other words, you'd almost definitely have to send a generation ship. Which means you'd have to have already figured things like artificial gravity, giving birth and raising children in space, etc. It wouldn't be too hard to imagine taking earth values for day/night and gravity, and then gradually over 50 years adjusting them so that, by the time you arrive, you'd have acclimatized to those values on the new world.
Also, nuclear sub crews live 18 hour days, so it's definitely doable.