I built what I believe to be the most sane way to "advertise" something: Let people buy directly from an image. This solves the problem of people not interested in the content, because of its unobtrusive nature -- if they don't hover over an item within the image, it's as if the "advertisement" isn't there.
Check out my demo (desktop only) at http://www.worldlifestyle.com/testpost
My website which you can sign up for the (free) beta at: http://pleenq.com