As someone that's also written hundreds of thousands of lines of assembly with macros I don't really see the comparison. Lisp macros are written in lisp itself. You can create complicated data structures, interate over loops, do file io, query databaes, access the network, whatever you want at compile time in lisp where as assembly language macros were never much more complicated than then the C preprocessor. I certaibly did tons of creative things with assembly language macros but they aren't remotely similar to lisp macros.
As for perf, 7 very popular and performant games were written in Lisp. Crash Bandicoot 1, 2, 3 as well as Jak and Daxter 1, 2, 3 and Racing.
As for perf, 7 very popular and performant games were written in Lisp. Crash Bandicoot 1, 2, 3 as well as Jak and Daxter 1, 2, 3 and Racing.