Firstly, on a personal note, I must say getting heavily downvoted on a factual statement and not an opinion is a new and confusing experience for me.
My comparisons were made several years ago using LAME 320 CBR, LAME VBR, OGG, lossless (WAV) 16bit 44.1kHz and lossless (WAV) 16bit 48kHz.
I believe at least most professional musicians and sound engineers would be able to identify the difference between all of these; while they might not always be "worse", their sonic character is certainly different.
My comparisons were made several years ago using LAME 320 CBR, LAME VBR, OGG, lossless (WAV) 16bit 44.1kHz and lossless (WAV) 16bit 48kHz. I believe at least most professional musicians and sound engineers would be able to identify the difference between all of these; while they might not always be "worse", their sonic character is certainly different.