Similar story here, from the POV of someone with moderate anxiety, and very mild depression (probably as a result of the anxiety). Medication made me feel less, which was preferable to anxiety, but CBT was a set of tools I've continued to use. I had so little insight into my own thought processes, and the ways in which I was unintentionally reinforcing my own anxieties. It's taken a lot of effort, over a lot of years, but with that basic set of tools I don't need medication and I don't have anxiety or panic attacks. Ever.
Still, if you did have that set of tools going in, but for whatever biological reason it didn't matter, then I would guess that CBT would be dust in the wind for you.
Still, if you did have that set of tools going in, but for whatever biological reason it didn't matter, then I would guess that CBT would be dust in the wind for you.