Tying profiling to political correctness means you want racial profiling or similar, which would have such a huge false negative and false positive rate as to be worse than useless. Besides, I'm sure the TSA already de facto does it, because sentiments like yours are so common.
If you want to profile, ignore political correctness and do it based on something other than race, religion, or national origin.
If you want to profile, ignore political correctness and do it based on something other than race, religion, or national origin.