What I do, when Chrome, or rather, my abuse of it (14 windows, 735 tabs at the moment, Ubuntu 14.04 64 bit on a 32 GiB system) becomes onerous is to go to the task manager and kill groups of tabs taking up "too much" memory, and very occasionally, too much CPU.
(I get away with that abuse, which it a bit higher right now because I'm in the process of buying a house, by killing all tabs after launching, and only enabling the ones I want, one by one, using the essential to me Session Buddy.)
(I get away with that abuse, which it a bit higher right now because I'm in the process of buying a house, by killing all tabs after launching, and only enabling the ones I want, one by one, using the essential to me Session Buddy.)