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Comment by MichaelBurge
I've been amazed that adblockers work on videos since I started using them. It seems like it wouldn't be much trouble at all to simply embed the ad in the video stream. It does let people skip past the ad, but I'm not sure how important that is. If they start doing that, you could do the heavy-handed approach of re-encoding the video to show the ad(or a spot for the ad to be filled in by the server) side-by-side and allow them to 'opt in' to the old Javascript solution by disabling their ad blocker.