For the vast majority of human history, work has always been something that was interwoven into our lives. From hunting and gathering, to farming and ranching, to woodworking and blacksmithing, and so on, up until the industrial revolution, nearly everyone "worked from home" and I'm unaware of any documented ill health effects from this. Intuitively, I'd suppose that aggregate stress levels actually rose with the advent of commuting to dedicated factory/office workplaces, as factory quotas and office micromanagement are far more psychologically demanding than the farm or home workshop in which you ( or your remote, usually undemanding lord, in the case of feudal work relationships ) set your own schedule and degree of competitiveness.
For the vast majority of human history, work has always been something that was interwoven into our lives. From hunting and gathering, to farming and ranching, to woodworking and blacksmithing, and so on, up until the industrial revolution, nearly everyone "worked from home" and I'm unaware of any documented ill health effects from this. Intuitively, I'd suppose that aggregate stress levels actually rose with the advent of commuting to dedicated factory/office workplaces, as factory quotas and office micromanagement are far more psychologically demanding than the farm or home workshop in which you ( or your remote, usually undemanding lord, in the case of feudal work relationships ) set your own schedule and degree of competitiveness.