As @fernly said, Qt is a cross-platform GUI library and htmlPy isn't bringing anything extra in that field.
htmlPy is meant for easy GUI development and integration with popular frameworks like Django for standalone app development. It adds to the memory usage of the application due to the use of QtWebkit.
If you are making a not-very-complex app and don't want to go to lot of trouble for making GUIs for standalone version, htmlPy is a great solution. But if your app is conservative about resources, doing lot of memory optimization or needs features which can't be done using HTML, probably best if you use native UI.
htmlPy is meant for easy GUI development and integration with popular frameworks like Django for standalone app development. It adds to the memory usage of the application due to the use of QtWebkit.
If you are making a not-very-complex app and don't want to go to lot of trouble for making GUIs for standalone version, htmlPy is a great solution. But if your app is conservative about resources, doing lot of memory optimization or needs features which can't be done using HTML, probably best if you use native UI.