"I for one would much rather use a plant, rather than opioids that cause addiction, physical dependence, and potentially a life-ruining downward spiral of misery."
Replace that with:
"I for one would much rather use a substance with no long-term side effects and generally considered safe, rather than opioids that..."
Replace that with:
"I for one would much rather use a substance with no long-term side effects and generally considered safe, rather than opioids that..."
:)